This study investigated the effects of varicocele on semen parameters in infertile men based on the new World Health Organization laboratory manual for the examination of human semen. Semen analysis results volume, sperm count, motility, and morphology were the primary outcomes. We searched articles published from to August , i. We included only those studies that reported the actual semen parameters of adult infertile men diagnosed with clinical varicocele and contained a control group of either fertile men or normozoospermic men who were not diagnosed with varicocele. Ten studies were included in the meta-analysis, involving men. Subgroup analyses indicated that the magnitude of effect was influenced by control subtype but not WHO laboratory manual edition used for semen assessment.
What is the link between varicocele and infertility?
Varicocele and infertility: Is there a link?
Smith, H. Kaune, D. Parodi, M. Madariaga, R. Rios, I. Morales, A. Oxidative stress and related sperm DNA damage have been identified as significant causes of male infertility.
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Forty-five patients with a mean age of Doppler Ultrasonography was performed to each individual in addition to physical examination. Semen analyses were performed by the same biologist. After routine semen analysis, the samples were fixed separately for further examination with AO staining.
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